Factors influencing platelet recovery after blood cell transplantation in multiple myeloma
نویسندگان
چکیده
منابع مشابه
Factors influencing extramedullary relapse after allogeneic transplantation for multiple myeloma
Patients undergoing allogeneic stem cell transplantation (allo-SCT) with reduced intensity conditioning (RIC) for multiple myeloma (MM) experience a high frequency of extra-medullary relapses (EMR) (20–37%). This study aims at determining factors predictive for EMR after allo-SCT, prognosis of EMR and efficacy of salvage therapies. We retrospectively analyzed a continuous cohort of 79 patients ...
متن کاملMULTIPLE MYELOMA Stem cell transplantation in multiple myeloma
High-dose treatment (HDT) with autologous stem cell transplantation (ASCT) has been shown to increase survival and time to progression in multiple myeloma (IMM) compared with conventional chemotherapy. In the French IFM90-study [1], 200 patients were randomised to receive prolonged standard treatment with i.v. combination chemotherapy, or a short phase by induction treatment with the same regim...
متن کاملSalvage therapy with thalidomide in multiple myeloma patients relapsing after autologous peripheral blood stem cell transplantation.
BACKGROUND AND OBJECTIVES The introduction of high-dose therapy with stem cell support has significantly improved the outcome of patients with multiple myeloma (MM) in terms of increased complete remission (CR) rate and extended survival, both disease-free and overall. Few options, however, are presently available for patients who relapse after single or double autologous stem cell transplantat...
متن کاملLenalidomide maintenance after stem-cell transplantation for multiple myeloma.
BACKGROUND High-dose chemotherapy with autologous stem-cell transplantation is a standard treatment for young patients with multiple myeloma. Residual disease is almost always present after transplantation and is responsible for relapse. This phase 3, placebo-controlled trial investigated the efficacy of lenalidomide maintenance therapy after transplantation. METHODS We randomly assigned 614 ...
متن کاملFactors influencing B lymphopoiesis after allogeneic hematopoietic cell transplantation.
In 93 allograft recipients, the numbers of marrow B-cell precursors on days 80 and 365 correlated with the counts of circulating B cells, suggesting that the posttransplantation B-cell deficiency is at least in part due to insufficient B lymphopoiesis. Factors that could affect B lymphopoiesis were evaluated. The number of marrow B-cell precursors on days 30 and 80 was at least 4-fold lower in ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 1997
ISSN: 0268-3369,1476-5365
DOI: 10.1038/sj.bmt.1700897